Sialic Acid Is Required for Neuronal Inhibition by Soluble MAG but not for Membrane Bound MAG
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منابع مشابه
Sialic Acid Is Required for Neuronal Inhibition by Soluble MAG but not for Membrane Bound MAG
Myelin-Associated Glycoprotein (MAG), a major inhibitor of axonal growth, is a member of the immunoglobulin (Ig) super-family. Importantly, MAG (also known as Siglec-4) is a member of the Siglec family of proteins (sialic acid-binding, immunoglobulin-like lectins), MAG binds to complex gangliosides, specifically GD1a and/or GT1b. Therefore, it has been proposed as neuronal receptors for MAG inh...
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ژورنال
عنوان ژورنال: Frontiers in Molecular Neuroscience
سال: 2016
ISSN: 1662-5099
DOI: 10.3389/fnmol.2016.00021